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Studies provide evidence of connections between MCI and negative health outcomes

2012-07-17 09:34:21
Two studies presented today at the Alzheimer's Association International Conference 2012 (AAIC 2012) in Vancouver provide evidence of connections between mild cognitive impairment (MCI) and negative health outcomes – increased isolation and death.

New CD141hi DC subset plays a critical role in activating immune response against pathogens

2012-07-17 09:34:21
Scientists at A*STAR's Singap ore Immunology Network (SIgN), in collaboration with Newcastle University, UK, the Singapore Institute of Clinical Sciences and clinicians from multiple hospitals in Singapore, have identified a new subset of dendritic cells (DCs) in human peripheral tissue which have a critical role in activating our immune response against harmful pathogens.

Obesity leads to more doctor visits than smoking

2012-07-17 09:34:21
Statistics show that today, almost one in four Canadians is obese. A deadly trend that has been on the rise for the last thirty years, obesity is associated with diabetes, heart disease and cancer. But is the obesity epidemic putting more pressure on an already strained Canadian health care system?

D-ribose effective in improving QOL in energy-depleted patients with FMS/CFS

2012-07-17 09:34:21
A new multi center study published in The Open Pain Journal showed that daily consumption of the pentose carbohydrate D-ribose resulted in an average energy boost of 61 percent among patients diagnosed with Chronic Fatigue Syndrome (CFS) and fibromyalgia (FMS).

Stress management treatment reduces formation of new brain lesions in people with MS

2012-07-17 09:34:21
Research conducted by Jesus Lovera, MD, Assistant Professor of Neurology at LSU Health Sciences Center New Orleans, and colleagues has shown that stress management treatment significantly reduced the formation of new brain lesions in people with multiple sclerosis (MS) over the course of treatment.

New automated method for identification of lung nodules in community-based settings

2012-07-17 09:34:21
Pulmonary nodules are common, but few studies of lung nodule ide ntification and clinical evaluation have been performed in community settings. Researchers from Kaiser Permanente Southern California identified 7,112 patients who had one or more nodules by using existing information within the electronic medical record.

InvivoSciences, WUSTL to construct artificial tissue models for heart failure

2012-07-17 09:34:21
The National Institutes of Health has awarded more than $2 million to a team of scientists from Washington University in St. Louis and InvivoSciences, a biotechnology startup with WUSTL roots, to construct artificial tissue models that will allow the rapid testing of new drugs for heart failure.

Targeting CDK1 pathway may be efficacious for acute myeloid leukemias with FLT3 mutation

2012-07-17 09:34:21
Acute myeloid leukemia, a common leukemia in adults, is charact erized by aberrant proliferation of cancerous bone marrow cells. Activating mutations in a protein receptor known as FLT3 receptor are among the most prevalent mutations observed in acute myeloid leukemias. FLT3 mutants are thought to activate several signaling pathways that contribute to cancer development.

MSU nursing researcher's Wii-Fit program helps lung cancer patients reduce fatigue

2012-07-17 12:33:16
With the support of a $379,741 grant from the National Cancer Institute and the Nintendo Wii game system, nursing researcher Amy Hoffman aims to help lung cancer patients reduce fatigue and get more exercise as they transition from the hospital to the home after surgery.

Tips to help minimize risks associated with acid reflux disease

2012-07-17 12:33:16
While the overall death rates from several cancers s uch as breast and lung have gone down, there has been a meteoric rise in cases of esophageal cancer. Studies have shown that from 1975 to 2001, the incidence of esophageal adenocarcinoma rose approximately sixfold in the United States (from four to 23 cases per million), a relative increase greater than that for melanoma, breast, or prostate cancer.

Why is the incidence of gout increasing?

2012-07-17 12:33:16
Gout has been described by the Daily Mail as something, "usually associated with port-swilling, over-fed elderly men of the 19th century". (1) Recent research carried out at the Boston University School of Medicine, however, has found that the incidence of gout in the US is on the rise. (2) Thus, the condition is clearly not something that only affects this stereotype.

Scientists discover new way to convert cord bl ood cells into iNC

2012-07-17 12:33:16
For more than 20 years, doctors have been using cells from blood that remains in the placenta and umbilical cord after childbirth to treat a variety of illnesses, from cancer and immune disorders to blood and metabolic diseases.

PsychoGenics, Afraxis partner to offer Enhanced Spine Platform technology

2012-07-17 12:33:16
Afraxis and PsychoGenics today announced an alliance to offer Afraxis' Enhanced Spine Platform (ESP) technology as part of PsychoGenics' comprehensive testing capabilities and drug discovery services.

Ampio announces advancement of NCE001 to preclinical development

2012-07-17 12:33:16
Ampio Pharmaceuticals, Inc., a biopharmaceutical company developing repurposed drugs and new molecular entities (NMEs) that treat inflammatory diseases, including osteoarthritis, diabetic macular edema (DME) and sexual dysfunction and conducting clinical trials on its four lead drugs announced today the advancement of NCE001, from its proprietary methylphenidate derivatives family of compounds, to preclinical development for the treatment of glioblastoma multiforme, renal cell carcinoma and inflammatory breast cancer following the granting of multiple composition of matter and use patents in the USA, Canada, Europe and China.

Scientists develop first cell-based model of Alzheimer's disease

2012-07-17 12:33:16
A team of scientists at The New York Stem Cell Foundation (NYSCF) Laboratory led by Scott Noggle, PhD, NYSCF-Charles Evans Senior Research Fellow for Alzheimer's Disease, has developed the first cell-based model of Alzheimer's disease (AD) by reprogramming skin cells of Alzheimer's patients to become brain cells that are affected in Alzheimer's.

VHVI now offers new minimally invasive, catheter-based approach to dissolve pulmonary embolism

2012-07-17 12:33:16
The Vanderbilt Heart and Vascular Institute (VHVI) now offers a minimally invasive, catheter-based approach to dissolving pulmonary embolism, a potentially life-threatening blood clot that form elsewhere in the body and travels into the lungs.

BRAF L597 mutation in melanoma patients responds to MEK inhibitor drugs

2012-07-17 12:33:16
An uncommon mutation of the BRAF gene in melanoma patients has been found to respond to MEK inhibitor drugs, providing a rationale for routine screening and therapy in melanoma patients who harbor the BRAF L597 mutation.

Genetic tests for Alzheimer's disease a comfort for the majority

2012-0 7-17 12:33:16
Several genetic tests are available for Alzheimer's disease, both for the general public and for those with a family history of the disease. As direct-to-consumer testing over the internet rises, so have concerns over how people will handle information related to their risk of developing Alzheimer's disease.

Anthera announces final set of clinical data from blisibimod Phase 2b study on SLE

2012-07-17 15:42:00
Anthera Pharmaceuticals, Inc., a biopharmaceutical company developing drugs to treat serious diseases associated with inflammation and autoimmune disorders, today announced the final set of clinical data from the Phase 2b PEARL-SC study in patients with systemic lupus erythematosus.

Pre-concussion baseline testing now available at three Vanderbilt clinics

2012-07-17 15:42:00
The Vander bilt Sports Concussion Center is now offering pre-concussion baseline testing to all community recreational athletes in advance of many high-impact seasonal sports resuming this fall.

Healthier levels of vitamin C can reduce inflammatory conditions

2012-07-17 15:42:00
The recommended dietary allowance, or RDA, of vitamin C is less than half what it should be, scientists argue in a recent report, because medical experts insist on evaluating this natural, but critical nutrient in the same way they do pharmaceutical drugs and reach faulty conclusions as a result.

High blood pressure associated with reduced mortality in extremely frail, elderly adults

2012-07-17 15:42:00
A new study suggests that higher blood pressure is associated with lower mortality in extremely frail, elderly adults.

Researchers begin to uncover important clues about SCAD

2012-07-17 15:42:00
Spontaneous coronary artery dissection (SCAD), a tear of the layers of the artery wall that can block normal blood flow into and around the heart, is a relatively rare and poorly understood condition. It often strikes young, otherwise healthy people -- mostly women -- and can lead to significant heart damage, even sudden death.

New Alzheimer's model derived from skin cells of patients may prove to be more accurate

2012-07-17 15:42:00
Researchers at the Alzheimer's Association International Conference 2012 (AAIC 2012) today reported the creation of a new model of Alzheimer's derived from the skin cells of people with the disease that were reprogramed into Alzheimer's brain cells.

Relationship bet ween two biological risk factors for schizophrenia

2012-07-17 15:42:00
Johns Hopkins researchers say they have discovered a cause-and-effect relationship between two well-established biological risk factors for schizophrenia previously believed to be independent of one another.

AstraZeneca plans to conduct ticagrelor plus clopidogrel clinical trial for PAD

2012-07-17 15:42:00
AstraZeneca today announced plans to conduct the EUCLID study, a global clinical trial involving 11,500 patients with peripheral artery disease (PAD), a condition affecting approximately 27 million people in Europe and North America.

Activating NOTCH and AKT gene may trigger cholangiocarcinoma

2012-07-17 15:42:00
A rare type of cancer thought to derive from cells in the bile ducts of the liver may actually develop when one type of liver cell morphs into a totally different type, a process scientists used to consider all but impossible. UCSF researchers triggered this kind of cellular transformation-and caused tumors to form in mice-by activating just two genes.

Ferring Pharmaceuticals receives FDA approval for new colon-cleansing drug

2012-07-17 21:33:47
On July 16, the U.S. Food and Drug Administration approved Prepopik (sodium picosulfate, magnesium oxide and citric acid) to help cleanse the colon in adults preparing for colonoscopy.

Promising path to Parkinson's disease treatment

2012-07-17 21:33:47
Using adult stem cells, Johns Hopkins researchers and a consortium of colleagues nationwide say they have generated the type of human neuron specifically damaged by Parkinson's disease (PD) and used various drugs to stop the damage.< br/>

Premier research institutions, Biogen Idec partner to sequence genomes of patients with ALS

2012-07-17 21:33:47
Biogen Idec today announced that it has entered into a research collaboration with premier academic and research institutions to sequence the genomes of up to 1,000 patients with amyotrophic lateral sclerosis (ALS) in an effort to gain a deeper understanding about the fundamental genetic causes of ALS.

Massage helps improve muscle health in athletes following exercise-induced injury

2012-07-17 21:33:47
New research proves the wide medical belief that massage helps improve muscle health in athletes following exercise-induced injury. Dr. Marvell Scott, sports medicine professional, provides further explanation on proper treatments.

WC MC receives NHLBI grant to study smoking-induced COPD

2012-07-17 21:33:47
Researchers at Weill Cornell Medical College were awarded a $6.5 million grant from the National Heart, Lung, and Blood Institute for a five-year investigation into metabolic changes occurring within airway epithelial cells in the lungs of chronic obstructive pulmonary disease (COPD) patients caused by cigarette smoking. In addition, researchers aim to identify which cigarette smokers are at highest risk of developing COPD as well as novel biomarkers to assist in the development of new therapeutic treatments for the disease.

Study shows why eating less may be therapeutic for people with neuromuscular disorders

2012-07-17 21:33:47
A novel technique for measuring tiny, rapid-fire secretions in the brains and mouthparts of fruit flies (drosophila) is providing insights into the beneficial effects of eating less - information that ultimately could help people suffering from neuromuscular disorders.

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Medical Condition News Feed

Positive results from Alnylam's ALN-TTR02 Phase I trial on TTR-mediated amyloidosis

2012-07-16 18:35:09
Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today the achievement of positive clinical results from its Phase I trial with ALN-TTR02, an RNAi therapeutic targeting the transthyretin (TTR) gene for the treatment of TTR-mediated amyloidosis.

FDA clears TMI's Glider PTCA balloon catheter

2012-07-16 18:35:09
TriReme Medical, Inc. (TMI) announced today that it has received FDA clearance for an expanded matrix of sizes for its unique Glider PTCA balloon catheter.

Merck to present results from clinical studies on BACE inhibitors at AAIC 2012

2012-07-16 18:35:09
Merck, known as MSD outside the United States and Canada, announced today presentations at the upcoming Alzheimer's Association International Conference (AAIC) being held in Vancouver, British Columbia, Canada on July 14-19, 2012.

St. Joseph Hospital initiates enrollment in Medtronic's SYMPLICITY HTN-3 trial for hypertension

2012-07-16 18:35:09
St. Joseph Hospital of Orange on July 11 enrolled its first patient as part of a national clinical trial conducted by Medtronic Inc. for a renal denervation procedure designed to eliminate treatment-resistant hypertension.

TV watching increases waist size and reduces sporting ability in children

2012-07-16 18:35:09
Each hour of TV watched by a two- to four-year- old contributes to his or her waist circumference by the end of grade 4 and his or her ability to perform in sports, according to a world-first study undertaken by researchers at the University of Montreal and its affiliated Saint-Justine Mother and Child University Hospital.

UMMS scientists identify new genetic mutation that causes familial ALS

2012-07-16 18:35:09
A new genetic mutation that causes familial amyotrophic lateral sclerosis (ALS), a fatal neurological disorder also known as Lou Gehrig's Disease, has been identified by a team of scientists led by researchers at the University of Massachusetts Medical School (UMMS).

UCB's Neupro now available in U.S. pharmacies

2012-07-16 18:35:09
UCB announced today that Neupro (Rotigotine Transdermal System) is now available in U.S. pharmacies. Neupro was approved by the U.S Food and Drug Administration in April to treat the signs and symptoms of early and advanced stage idiopathic Parkinson's disease and moderate-to-severe primary Restless Legs Syndrome.

Study determines optimal screening strategy for gastric or stomach cancer

2012-07-16 18:35:09
A new study has determined how often people should get screened for gastric or stomach cancer in high-risk regions of the world. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings could help reduce deaths from gastric cancer, which is the second most common cause of cancer-related mortality.

New surgical t echnique may repair common, painful hip condition in elite athletes

2012-07-16 18:35:09
A common, painful hip condition in elite athletes may be able to be repaired with an improved surgical technique, according to researchers presenting their work at the American Orthopaedic Society for Sports Medicine's Annual Meeting in Baltimore, Maryland today.

Novel way to monitor real-time chemical changes in brains of patients undergoing DBS

2012-07-16 18:35:09
Mayo Clinic researchers have found a novel way to monitor real-time chemical changes in the brains of patients undergoing deep brain stimulation (DBS). The groundbreaking insight will help physicians more effectively use DBS to treat brain disorders such as Parkinson's disease, depression and Tourette syndrome.

Osteoporosis and sarcopenia: researchers at UMKC rece ive $8.3 million to study relationship

2012-07-16 21:34:03
The University of Missouri-Kansas City has received a five-year, $8.3 million grant from the National Institute on Aging, part of the National Institutes of Health, to study the relationship between osteoporosis (loss of bone density) and sarcopenia (loss of muscle mass) as people age.

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Public Policy Connections: YouTube Sends Users To Copyright School: Should Content Owners Have to Go, Too?

 

YouTube Sends Users To Copyright School: Should Content Owners Have to Go, Too?

Google has faced mounting criticism from lawmakers and the entertainment industry for not doing enough to combat online copyright infringement, and on April 14 released a set of stricter copyright policies for YouTube online video users.  Copyright policy violators will be required to watch a "copyright tutorial" and pass a test before allowing them to continue using the service.

A posting by the Electronic Frontier Foundation (EFF) digs deeper into the issues, crediting YouTube for doing the right thing by jettisoning its one-size-fits-all three strikes termination policy, while also questioning  requiring users who receive takedown notices to go to “copyright school," and that school has a pretty misleading curriculum. EFF makes the point that if YouTube is going to ask users to learn more about copyright when they receive a takedown notice, they should require the same of right-holders whose takedowns are disputed. As we have been reminded all too often, many content owners are badly in need of copyright education.

Read POLITICO Pro news story: Google unveils 'copyright school"
Read EFF news story: YouTube Sends Users To Copyright School: Will Content Owners Have to Go, Too?
Read LA Times news story:  YouTube to require 'tutorials' for copyright offenders

Public Policy Connections: YouTube Sends Users To Copyright School: Should Content Owners Have to Go, Too?

SPARC introduces Open-access Journal Publishing Resource Index

New resource helps streamline launch and operation of open-access journals.

Washington, D.C. -- SPARC (the Scholarly Publishing and Academic
Resources Coalition) today released a free online Open Access
Journal Publishing Resource Index with information and documents
to support the launch and operation of an open-access journal.
Materials in the index will help libraries, presses, and other
academic units on campuses as they work together to make the work
of their researchers more widely available.

This new resource is launched in conjunction with the SPARC
Campus-based Publishing Resource Center
(http://www.arl.org/sparc/partnering), which delivers a guide to
critical issues in campus-based publishing partnerships, case
studies, a bibliography and resource list, an index of
collaborative initiatives (operated in partnership with Columbia
University Libraries), and access to the LIBPRESS online
discussion forum (operated by the University of California). The
Center is overseen by an editorial board representing library and
university press staff who are actively engaged in creating and
managing publishing partnerships.

The new index complements the rich existing resource center by
pointing to relevant sections in existing open-access journal
publishing guides and to sample journal proposals, policies,
bylaws, and other documentation to help with planning,
development, and collaboration issues. Topics covered include:

* New Journal Planning
* Journal Publishing Program Policies
* Governance
* Editorial
* Marketing & Promotion
* Technical Platforms
* Sustainability Planning

Relevant sections of existing open-access publishing guides,
including those by David Solomon, Carol Sutton, Kevin Stranack,
Jan Velterop, Howard Goldstein and Raym Crow, and others are
indicated under each topic area.

By highlighting samples and best practices, the index will help
give campuses the tools they need to develop and maintain
long-term, successful open-access publishing ventures. "As
campus-based publishing gets more ambitious in scope, it's
important to build on the successes and challenges of earlier
initiatives and adopt best practices," said Raym Crow, senior
consultant at SPARC. "Ultimately, campus-based publishing can
offer universities greater control over the intellectual products
they help create. SPARC is pleased to provide another tool to
support libraries and publishers in sustainable, professional,
open-access publishing."

Lee C. Van Orsdel, Dean of University Libraries at Grand Valley
State University, says faculty are beginning to consult
librarians for advice on journal publishing options, including
open-access models, and the SPARC site is a welcome resource.
"We're deepening our knowledge as quickly as possible, but it's a
whole new area of expertise for most of us," she said. "It will
save us time and increase the probability that we can get to the
right solution when advising our faculty on their best options."

The editorial board invites contributions from other campuses to
help build this resource and expand the bibliography --
especially with primary research papers on collaboration issues.
"SPARC hopes this will seed an effort where people will give
documents to share, making it a community hub," said Crow.
Members of the board and how to contact the managing editor with
suggestions are detailed on the Center home page.

The Open Access Journal Publishing Resource Index is available
online at http://www.arl.org/sparc/partnering.